Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E genotype and its effect on duration and severity of early and late onset Alzheimer's disease.

The British journal of psychiatry : the journal of mental science - 1 Oct 1995

Norrman J, Brookes A J, Yates C, St Clair D

Abstract excerpt

BACKGROUND: The apolipoprotein E (ApoE) epsilon 4 allele is associated with an increased risk of senile and probably presenile Alzheimer's disease. It is not yet clear whether the epsilon 4 allele also influences the duration/rate of progress of illness and the severity of the dementia. METHOD: We have retrospectively examined a series of ApoE genotyped presenile and senile autopsy cases of Alzheimer's disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Gene Frequency

Share to Genotype

Source

Identifiers

PMID: 8829725
DOI: 10.1192/bjp.167.4.533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E genotype and its effect on duration and severity of early and late onset Alzheimer's disease.PMID 8829725Read ↗

Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study.Semantic proximity Read ↗

Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E epsilon4 allele is unrelated to cognitive or functional decline in Alzheimer's disease: retrospective and prospective analysis.Semantic proximity Read ↗

Apolipoprotein E genotype and rate of decline in probable Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease.Semantic proximity Read ↗

The role of APOE polymorphisms in late-onset dementias.Semantic proximity Read ↗

Alzheimer's disease: clinical implications of the apolipoprotein E genotype.Semantic proximity Read ↗

[The apolipoprotein E-epsilon 4 allele is a risk factor for Alzheimer disease with early and late onset].Semantic proximity Read ↗

Apolipoprotein E genotype in the prediction of cognitive decline and dementia in a prospectively studied elderly population.Semantic proximity Read ↗

Apolipoprotein E epsilon 4, other risk factors, and course of Alzheimer's disease.Semantic proximity Read ↗

Clinical and neuropathological correlates of apolipoprotein E genotype in Alzheimer's disease. Window on molecular epidemiology.Semantic proximity Read ↗

Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.