Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease.

doi:10.1016/0304-3940(94)11107-t

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Article

Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease.

Neuroscience letters - 2 Jan 1995

Basun H, Grut M, Winblad B, Lannfelt L

Abstract excerpt

A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. The epsilon 4 allele carriers had a significantly lower age of disease onset compared to non-epsilon 4 carriers. How...

Topics

Age of Onset
Aged
Aged, 80 and over
Alzheimer Disease
Apolipoproteins E
Disease Progression
Female
Follow-Up Studies
Genotype
Humans
Male
Psychiatric Status Rating Scales

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