Article
Apolipoprotein epsilon 4 allele and disease progression in patients with late-onset Alzheimer's disease.
Neuroscience letters - 2 Jan 1995
Basun H, Grut M, Winblad B, Lannfelt L
Abstract excerpt
A random sample of 60 late-onset Alzheimer's disease (AD) cases from a population-based study were apolipoprotein E (apoE) genotyped and clinically examined with a 3-year interval. The epsilon 4 allele carriers had a significantly lower age of disease onset compared to non-epsilon 4 carriers. However, no significant differences were observed between epsilon 4 allele carries and non-carriers for Mini-Mental State...
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