Article
Alzheimer's disease: clinical implications of the apolipoprotein E genotype.
Neurology - 1 May 1997
Farlow M R
Abstract excerpt
Inheritance of the apolipoprotein E (APOE = gene; apoE = protein) epsilon 4 gene is associated with a higher risk for development of Alzheimer's disease (AD) and for occurrence of this illness at a younger age. APOE gene dose and genotype interact with gender, ethnicity, and age to influence the probability of developing AD, as well as the rate of disease progression. The sensitivity and specificity of APOE...
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