Article
Apolipoprotein E epsilon 4, other risk factors, and course of Alzheimer's disease.
Biological psychiatry - 1 Mar 1999
Weiner M F, Vega G, Risser R C, Honig L S, Cullum C M, Crumpacker D, Rosenberg R N
Abstract excerpt
BACKGROUND: The epsilon 4 allele of apolipoprotein E (apoE epsilon 4) is associated with late-onset Alzheimer's disease (AD), but its relationship to various aspects of AD has become increasingly unclear. We studied the relationship of apoE genotype in AD to educational attainment, history of heart disease or head injury, age of onset, gender, severity of illness, depression, psychotic symptoms, rate of dementia...
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