Article
Screening for linkage and association in nuclear families.
Genetic epidemiology - 1 Jan 1995
Knapp M, Durner M, Baur M P
Abstract excerpt
We applied linkage analysis with a sib-pair method, which also takes into account information on unaffected siblings, and family-based methods of association analysis to determine the disease affecting loci in Problem 1. Whereas the first two disease loci were correctly identified by association analysis, the sib-pair linkage method failed to detect the disease loci 3 and 4. We therefore determined the data...
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