Search for susceptibility genes, gene x gene interactions, and gene x environment interactions utilizing nonparametric linkage analysis.

doi:10.1002/gepi.1370170787

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Article

Search for susceptibility genes, gene x gene interactions, and gene x environment interactions utilizing nonparametric linkage analysis.

Genetic epidemiology - 1 Jan 1999

Ehm M G, Karnoub M C, St Jean P

Abstract excerpt

There may be a different genetic basis for the two forms of the disease simulated in Problem 2 and the complex disease may be affected by environmental factors. Hence, we investigate the effects of two environmental factors. We selected 400 nuclear families from the data generated for Problem 2. Affection status was investigated in several ways. Individuals with severe and mild forms of the disease were both...

Topics

Environment
Epistasis, Genetic
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Genetic Testing
Genetic Variation
Humans
Models, Genetic
Software
Statistics, Nonparametric

Source

Open in PubMed

Identifiers

PMID: 10597489
DOI: 10.1002/gepi.1370170787

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