Article
A comparative study of sibship tests of linkage and/or association.
American journal of human genetics - 1 Nov 1998
Monks S A, Kaplan N L, Weir B S
Abstract excerpt
Population-based tests of association have used data from either case-control studies or studies based on trios (affected child and parents). Case-control studies are more prone to false-positive results caused by inappropriate controls, which can occur if, for example, there is population admixture or stratification. An advantage of family-based tests is that cases and controls are well matched, but parental...
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