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Article

Interpretation of simultaneous linkage and family-based association tests in genome screens.

Genetic epidemiology - 1 Feb 2007

Chung Ren-Hua, Hauser Elizabeth R, Martin Eden R

Abstract excerpt

Linkage and association analyses have played important roles in identifying susceptibility genes for complex diseases. Linkage tests and family-based tests of association are often applied in the same data to help fine-map disease loci or validate results. This paradigm increases efficiency by making maximal use of family data sets. However, it is not intuitively clear under what conditions association and...

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PMID: 17123303
DOI: 10.1002/gepi.20196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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