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Article

Interpretation of simultaneous linkage and family-based association tests in genome screens.

Genetic epidemiology - 1 Feb 2007

Chung Ren-Hua, Hauser Elizabeth R, Martin Eden R

Abstract excerpt

Linkage and association analyses have played important roles in identifying susceptibility genes for complex diseases. Linkage tests and family-based tests of association are often applied in the same data to help fine-map disease loci or validate results. This paradigm increases efficiency by ma...

Topics

Alleles
Chromosome Mapping
Computer Simulation
Female
Genetic Markers
Genome, Human
Genotype
Humans
Linkage Disequilibrium
Male
Models, Genetic
Nuclear Family
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prevalence

Siblings

Statistical Distributions

Source

Identifiers

PMID: 17123303
DOI: 10.1002/gepi.20196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-17123303-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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