Article
Validity, efficiency, and robustness of a family-based test of association.
Genetic epidemiology - 1 Jan 2006
Lewinger Juan Pablo, Bull Shelley B
Abstract excerpt
We propose a new test of linkage in the presence of allelic association that uses all available information in a sample of nuclear families, including parental phenotypes, genotypes from both affected and unaffected siblings, and families with homozygous parents. The test is based on the conditional framework developed by Rabinowitz and Laird [2000: Hum Hered 50:211-223] and is thus immune to population...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.