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Article

Tests for linkage and association in nuclear families.

American journal of human genetics - 1 Aug 1997

Martin E R, Kaplan N L, Weir B S

Abstract excerpt

The transmission/disequilibrium test (TDT) originally was introduced to test for linkage between a genetic marker and a disease-susceptibility locus, in the presence of association. Recently, the TDT has been used to test for association in the presence of linkage. The motivation for this is that linkage analysis typically identifies large candidate regions, and further refinement is necessary before a search for...

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Identifiers

PMID: 9311750
DOI: 10.1086/514860
PMCID: PMC1715892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Tests for linkage and association in nuclear families.PMID 9311750Read ↗

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Power calculations for a general class of tests of linkage and association that use nuclear families with affected and unaffected sibs.Semantic proximity Read ↗

Linkage and association.Semantic proximity Read ↗

Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal.Semantic proximity Read ↗

Family-based tests of association and/or linkage.Semantic proximity Read ↗

Single Marker Family-Based Association Analysis Conditional on Parental Information.Semantic proximity Read ↗

Transmission/disequilibrium test when neither parent is available in some families: a non-iterative approach.Semantic proximity Read ↗

Screening for linkage and association in nuclear families.Semantic proximity Read ↗

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