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Article

Genotype relative-risks and association tests for nuclear families with missing parental data.

Genetic epidemiology - 1 Jan 1997

Schaid D J, Li H

Abstract excerpt

The development of a new method for testing the association of genetic markers with disease is presented. This approach is applicable when sampling nuclear families with one or more affected siblings and when neither, one, or both parents are missing marker genotype data. All siblings, affected and not affected, are used to probabilistically infer the missing parental marker data. A likelihood ratio statistic,...

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Identifiers

PMID: 9433633
DOI: 10.1002/(SICI)1098-2272(1997)14:6<1113::AID-GEPI92>3.0.CO;2-J

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