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Article

Identifying susceptibility genes using linkage and linkage disequilibrium analysis in large pedigrees.

Genetic epidemiology - 1 Jan 2001

Meng Z, Zaykin D V, Karnoub M C, Sreekumar G P, St Jean P L, Ehm M G

Abstract excerpt

Linkage and linkage disequilibrium tests are powerful tools for mapping complex disease genes. We investigated two approaches to identifying markers associated with disease. One method applied linkage analysis and then linkage disequilibrium tests to markers within linked regions. The other method looked for linkage disequilibrium with disease using all markers. Additionally, we investigated using Simes' test to...

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Identifiers

PMID: 11793718
DOI: 10.1002/gepi.2001.21.s1.s453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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