Article
Evidence for limited B-lymphopoiesis in adult rabbits.
The Journal of experimental medicine - 1 May 1996
Crane M A, Kingzette M, Knight K L
Abstract excerpt
Rabbits are born with a limited VDJ gene repertoire formed primarily by rearrangement of one VH gene, VH1. The VDJ genes are undiversified at birth but become diversified by approximately 2 mo of age. To investigate more closely the time during which this diversity occurs, we determined the nucleotide sequences of VDJ genes from peripheral blood leukocytes taken from young rabbits at various time points, and we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
