Article
Diversification of rabbit VH genes by gene-conversion-like and hypermutation mechanisms.
Immunological reviews - 1 Apr 1998
Mage R G
Abstract excerpt
Where, when and how does VH diversification occur in the rabbit? Early diversification by gene-conversion and somatic hypermutation in rabbit appendix and chicken bursa of Fabricius are similar processes; the chicken bursa and the rabbit appendix have homologous functions. However, diversification in bursa starts during embryonic development whereas it starts in rabbit appendix about 2 weeks after birth in the...
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