A two-step mechanism for 5' and 3' splice-site pairing.

doi:10.1038/375510a0

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Article

A two-step mechanism for 5' and 3' splice-site pairing.

Nature - 8 Jun 1995

Chiara M D, Reed R

Abstract excerpt

A fundamental question in the splicing of precursor messenger RNA is how the 5' and 3' splice sites are recognized and paired during the splicing reaction. It has been proposed that spliceosome assembly in metazoan pre-mRNAs can be initiated through interaction between the 3' splice site and spec...

Topics

Animals
Base Sequence
Binding Sites
Exons
Introns
Molecular Sequence Data
Mutation
Plasmids
RNA Precursors
RNA Splicing
Ribonucleoproteins, Small Nuclear

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