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Article

European and US Guideline-Based Statin Eligibility, Genetically Predicted Coronary Artery Disease, and the Risk of Major Coronary Events.

Journal of the American Heart Association - 7 May 2024

Park Hanjin, Kim Daehoon, You Seng Chan, Jang Eunsun, Yu Hee Tae, Kim Tae-Hoon, Kim Dong-Min, Sung Jung-Hoon, Pak Hui-Nam, Lee Moon-Hyoung, Yang Pil-Sung, Joung Boyoung

Abstract excerpt

BACKGROUND: A study was designed to investigate whether the coronary artery disease polygenic risk score (CAD-PRS) may guide lipid-lowering treatment initiation as well as deferral in primary prevention beyond established clinical risk scores. METHODS AND RESULTS: Participants were 311 799 individuals from the UK Biobank free of atherosclerotic cardiovascular disease, diabetes, chronic kidney disease, and...

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Identifiers

PMID: 38639378
DOI: 10.1161/JAHA.123.032831
PMCID: PMC11179899

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CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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