Article

Effect of disclosing a polygenic risk score for coronary heart disease on adverse cardiovascular events: 10-year follow-up of the MI-GENES randomized clinical trial

2024-07-19

Abstract excerpt

<h4>Background</h4> The MI-GENES clinical trial ( NCT01936675 ), in which participants at intermediate risk of coronary heart disease (CHD) were randomized to receive a Framingham risk score (FRS g , n=103), or an integrated risk score (IRS g , n=104) that additionally included a polygenic risk score (PRS), demonstrated that after 6 months, participants randomized to IRS g had higher statin initiation and low...

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Literature Corpus work: c44b9543-de24-5418-9e4e-5ceee0d81fd2
DOI: 10.1101/2024.07.19.24310709

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