Article

Polygenic risk score and statin relative risk reduction for primary prevention in a real-world population

2021-07-29

Abstract excerpt

<h4>Abstracts</h4> <h4>Background</h4> Randomized-controlled trials demonstrate that high coronary heart disease (CHD) polygenic risk score modifies statin CHD relative risk reduction, but it is unknown if the association extends to statin users undergoing routine care. <h4>Objectives</h4> The primary objective was to determine how statin effectiveness is modified by CHD polygenic risk score in a real-world coh...

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Literature Corpus work: fd868f0f-8caa-51d3-bfc8-ba367a426ec1
DOI: 10.1101/2021.07.28.21254571

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