Article
Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors.
Circulation. Genomic and precision medicine - 1 Oct 2022
Ramírez Julia, van Duijvenboden Stefan, Young William J, Tinker Andrew, Lambiase Pier D, Orini Michele, Munroe Patricia B
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) and major adverse cardiovascular events (MACE) are the leading causes of death in the general population, but risk stratification remains suboptimal. CAD genetic risk scores (GRSs) predict risk independently from clinical tools, like QRISK3. We assessed the added value of GRSs for a variety of cardiovascular traits (CV GRSs) for predicting CAD and MACE and tested their...
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