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Article

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French Canadians

1 Jun 2019

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) represents one of the leading causes of morbidity and mortality worldwide. Given the healthcare risks and societal impacts associated with CAD, their clinical management would benefit from improved prevention and prediction tools. Polygenic risk scores (PRS) based on an individual's genome sequence are emerging as potentially powerful biomarkers to predict the risk to...

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PMID: 31184202
DOI: 10.1161/circgen.119.002481

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