Article

Validation of genome-wide polygenic risk scores for coronary artery disease in French Canadians

2019-02-05

Abstract excerpt

Coronary artery disease (CAD) represents one of the leading causes of morbidity and mortality worldwide. Given the healthcare risks and societal impacts associated with CAD, their clinical management would benefit from improved prevention and prediction tools. Polygenic risk scores (PRS) based on an individual’s genome sequence are emerging as potentially powerful biomarkers to predict the risk to develop CAD. Two...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1cc9f82d-1acc-5a9b-b031-898a6122ddd4
DOI: 10.1101/538470

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Validation of genome-wide polygenic risk scores for coronary artery disease in French CanadiansDOI 10.1101/538470Read

Validation of Genome-Wide Polygenic Risk Scores for Coronary Artery Disease in French CanadiansSemantic proximity Read

Development of an Integrated Monogenic and Polygenic Risk Assessment Tool for Coronary Artery Disease and Its Application in a Community-Based Health Care Biobank.Semantic proximity Read

A multi-ancestry polygenic risk score improves risk prediction for coronary artery disease.Semantic proximity Read

Monogenic and Polygenic Models of Coronary Artery Disease.Semantic proximity Read

Genome-wide polygenic score to identify a monogenic risk-equivalent for coronary diseaseSemantic proximity Read

Genomic risk prediction of coronary artery disease in nearly 500,000 adults: implications for early screening and primary preventionSemantic proximity Read

Polygenic Hyperlipidemias and Coronary Artery Disease RiskSemantic proximity Read

Association of Genetically Predicted Levels of Circulating Blood Lipids with Coronary Artery Disease IncidenceSemantic proximity Read

Polygenic risk scores in coronary artery disease.Semantic proximity Read

Polygenic Risk for Coronary Artery Disease in the Scottish and English PopulationSemantic proximity Read

Polygenic risk for coronary artery disease in the Scottish and English population.Semantic proximity Read

Polygenic Risk Score Modifies Risk of Coronary Artery Disease Conferred by Low-Density Lipoprotein CholesterolSemantic proximity Read