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Article

RAD21 mutations in acute myeloid leukemia.

Leukemia & lymphoma - 1 Jul 2024

Laczko Dorottya, Poveda-Rogers Corey, Matthews Andrew H, Snaith Oraine, Luger Selina, Bagg Adam, Caponetti Gabriel C, Morrissette Jennifer J D, Yang Guang

Abstract excerpt

The cohesin complex is a ring-shaped protein structure involved in DNA repair and chromosomal segregation. Studies have showed that genomic alterations in the cohesin complex members are among the initial occurrences in the development of acute myeloid leukemia (AML). STAG2 is the most commonly mutated and best-studied member of the cohesin complex in AML and mutations in this gene have been associated with...

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Source

Identifiers

PMID: 38506144
DOI: 10.1080/10428194.2024.2328233

Genes

RAD21
CD7
STAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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