Article
Mutations in the cohesin complex in acute myeloid leukemia: clinical and prognostic implications.
Blood - 6 Feb 2014
Thol Felicitas, Bollin Robin, Gehlhaar Marten, Walter Carolin, Dugas Martin, Suchanek Karl Josef, Kirchner Aylin, Huang Liu, Chaturvedi Anuhar, Wichmann Martin, Wiehlmann Lutz, Shahswar Rabia, Damm Frederik, Göhring Gudrun, Schlegelberger Brigitte, Schlenk Richard, Döhner Konstanze, Döhner Hartmut, Krauter Jürgen, Ganser Arnold, Heuser Michael
Abstract excerpt
Mutations in the cohesin complex are novel, genetic lesions in acute myeloid leukemia (AML) that are not well characterized. In this study, we analyzed the frequency, clinical, and prognostic implications of mutations in STAG1, STAG2, SMC1A, SMC3, and RAD21, all members of the cohesin complex, in...
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