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Article

Cohesin mutations in myeloid malignancies made simple.

Current opinion in hematology - 1 Mar 2018

Viny Aaron D, Levine Ross L

Abstract excerpt

PURPOSE OF REVIEW: Recurrent loss of function mutations within genes of the cohesin complex have been identified in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). STAG2 is the most commonly mutated cohesin member in AML as well as solid tumors. STAG2 is recurrently, mutated in Ewing's Sarcoma, bladder cancer, and glioblastoma, and is one of only ten genes known to be recurrently mutated in over...

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Share to Antigens, Nuclear
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hematologic Neoplasms

Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 29278534
DOI: 10.1097/MOH.0000000000000405
PMCID: PMC6601335

Genes

STAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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