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Article

Conformational Effects of a Cancer-Linked Mutation in Pri-miR-30c RNA.

Journal of molecular biology - 30 Sept 2022

Jones Alisha N, Walbrun Andreas, Falleroni Fabio, Rief Matthias, Sattler Michael

Abstract excerpt

MicroRNAs (miRNAs) are small, noncoding RNAs that mediate post-transcriptional downregulation of specific target genes. These transcripts are the products of a two-step processing pathway; primary miRNAs (pri-miRNAs) are processed by Drosha into individual precursor miRNA (pre-miRNA) hairpins, which are subsequently processed by Dicer into mature miRNAs. Single nucleotide polymorphisms (SNPs) that occur in...

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Identifiers

PMID: 35760371
DOI: 10.1016/j.jmb.2022.167705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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