Article
PCNA promotes context-specific sister chromatid cohesion establishment separate from that of chromatin condensation.
Cell cycle (Georgetown, Tex.) - 1 Oct 2020
Zuilkoski Caitlin M, Skibbens Robert V
Abstract excerpt
Cellular genomes undergo various structural changes that include cis tethering (the tethering together of two loci within a single DNA molecule), which promotes chromosome condensation and transcriptional activation, and trans tethering (the tethering together of two DNA molecules), which promotes sister chromatid cohesion and DNA repair. The protein complex termed cohesin promotes both cis and trans forms of DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
