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Article

Functional control of Eco1 through the MCM complex in sister chromatid cohesion.

Gene - 5 Jun 2021

Yoshimura Atsunori, Sutani Takashi, Shirahige Katsuhiko

Abstract excerpt

Sister chromatid cohesion (SCC) is essential for the maintenance of genome integrity. The establishment of SCC is coupled to DNA replication, and this is achieved in budding yeast Saccharomyces cerevisiae by a mechanism that is dependent on the interaction between Eco1 acetyltransferase and PCNA in the DNA replication complex. In vertebrates, the Eco1 homolog ESCO2 has been reported to interact with MCM complex...

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Identifiers

PMID: 33753149
DOI: 10.1016/j.gene.2021.145584

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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