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Article

Cohesin-independent segregation of sister chromatids in budding yeast.

Molecular biology of the cell - 1 Feb 2012

Guacci Vincent, Koshland Douglas

Abstract excerpt

Cohesin generates cohesion between sister chromatids, which enables chromosomes to form bipolar attachments to the mitotic spindle and segregate. Cohesin also functions in chromosome condensation, transcriptional regulation, and DNA damage repair. Here we analyze the role of acetylation in modulating cohesin functions and how it affects budding yeast viability. Previous studies show that cohesion establishment...

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Share to Acetylation
Share to Acetyltransferases
Share to Chromatids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomal Proteins, Non-Histone

Share to Chromosome Segregation

Share to Chromosomes, Fungal

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Share to Spindle Apparatus

Source

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Identifiers

PMID: 22190734
DOI: 10.1091/mbc.E11-08-0696
PMCID: PMC3279399

Genes

SMC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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