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An identification and functional evaluation of a novel CYP2C9 variant CYP2C9*62.

Chemico-biological interactions - 25 Aug 2020

Chen Hao, Dai Da-Peng, Zhou Shan, Liu Jian, Wang Shuang-Hu, Wu Hua-Lan, Zhou Quan, Geng Pei-Wu, Chong Jia, Lü You, Cai Jian-Ping, Yang Jie-Fu

Abstract excerpt

Warfarin is the most commonly used anticoagulant in the clinical treatment of thromboembolic diseases. The dose of warfarin varies significantly within populations, and the dose is closely related to the genetic polymorphisms of the CYP2C9 and VKORC1 genes. In this study, a new CYP2C9 nonsynonymous mutation (8576C > T) was detected after the genetic screening of 162 patients took warfarin. This mutation, named as...

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PMID: 32531309
DOI: 10.1016/j.cbi.2020.109168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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