Article
Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans.
Molecular pharmacology - 1 Aug 2001
Dickmann L J, Rettie A E, Kneller M B, Kim R B, Wood A J, Stein C M, Wilkinson G R, Schwarz U I
Abstract excerpt
CYP2C9 is a polymorphic gene for which there are four known allelic variants; CYP2C9*1, CYP2C9*2, CYP2C9*3, and CYP2C9*4. In the present study, DNA from 140 European Americans and 120 African Americans was examined by single-strand conformational polymorphism and restriction fragment length polymorphism analyses, resulting in the identification of a new CYP2C9 variant, CYP2C9*5. This variant is derived from a...
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