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Article

Characterization of the novel defective CYP2C9*24 allele.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jun 2007

Herman Darja, Dolzan Vita, Ingelman-Sundberg Magnus

Abstract excerpt

CYP2C9 is one of the major drug-metabolizing enzymes, and it is involved in the oxidative metabolism of approximately 10% of clinically important drugs, among which some, such as the anticoagulant warfarin, have a narrow therapeutic index. The human CYP2C9 gene is highly polymorphic. We found a new sequence variation in exon 7 of the CYP2C9 gene (1060G>A) resulting in a substitution of acidic amino acid glutamate...

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Identifiers

PMID: 17332144
DOI: 10.1124/dmd.106.013722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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