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Article

Schizophrenia polygenic risk score and 20-year course of illness in psychotic disorders.

Translational psychiatry - 14 Nov 2019

Jonas Katherine G, Lencz Todd, Li Kaiqiao, Malhotra Anil K, Perlman Greg, Fochtmann Laura J, Bromet Evelyn J, Kotov Roman

Abstract excerpt

Understanding whether and how the schizophrenia polygenic risk score (SZ PRS) predicts course of illness could improve diagnosis and prognostication in psychotic disorders. We tested whether the SZ PRS predicts symptoms, cognition, illness severity, and diagnostic changes over the 20 years following first admission. The Suffolk County Mental Health Project is an inception cohort study of first-admission patients...

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Identifiers

PMID: 31727878
DOI: 10.1038/s41398-019-0612-5
PMCID: PMC6856168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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