Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders.

doi:10.1038/s41380-024-02516-6

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Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders.

Molecular psychiatry - 1 Sept 2024

Kämpe Anders, Suvisaari Jaana, Lähteenvuo Markku, Singh Tarjinder, Ahola-Olli Ari, Urpa Lea, Haaki Willehard, Hietala Jarmo, Isometsä Erkki, Jukuri Tuomas, Kampman Olli, Kieseppä Tuula, Lahdensuo Kaisla, Lönnqvist Jouko, Männynsalo Teemu, Paunio Tiina, Niemi-Pynttäri Jussi, Suokas Kimmo, Tuulio-Henriksson Annamari, Veijola Juha, Wegelius Asko, Daly Mark, Taylor Jacob, Kendler Kenneth S, Palotie Aarno, Pietiläinen Olli

Abstract excerpt

Genetic factors contribute to the susceptibility of psychotic disorders, but less is known how they affect psychotic disease-course development. Utilizing polygenic scores (PGSs) in combination with longitudinal healthcare data with decades of follow-up we investigated the contributing genetics to psychotic disease-course severity and diagnostic shifts in the SUPER-Finland study, encompassing 10 403 genotyped...

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PMID: 38556557
DOI: 10.1038/s41380-024-02516-6
PMCID: PMC11420086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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