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Article

Schizophrenia polygenic risk score in psychosis proneness.

European archives of psychiatry and clinical neuroscience - 1 Dec 2023

Mas-Bermejo Patricia, Papiol Sergi, Via Marc, Rovira Paula, Torrecilla Pilar, Kwapil Thomas R, Barrantes-Vidal Neus, Rosa Araceli

Abstract excerpt

Schizophrenia (SZ) is a complex disorder with a highly polygenic inheritance. It can be conceived as the extreme expression of a continuum of traits that are present in the general population often broadly referred to as schizotypy. However, it is still poorly understood how these traits overlap genetically with the disorder. We investigated whether polygenic risk for SZ is associated with these disorder-related...

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Identifiers

PMID: 37301774
DOI: 10.1007/s00406-023-01633-7
PMCID: PMC10713704

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