Article

Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four healthcare systems

2018-09-18

Abstract excerpt

<h4>OBJECTIVE</h4> Individuals at high risk for schizophrenia may benefit from early intervention but few validated risk predictors are available. Genetic profiling is one approach to risk stratification that has been extensively validated in research cohorts, but its utility in clinical settings remains largely unexplored. Moreover, the broad health consequences of a high genetic risk of schizophrenia are poorly...

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Literature Corpus work: 3e89a591-b763-50f6-8927-9dad74a27e19
DOI: 10.1101/421164

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