Article
Multiple Nonsense-Mediated mRNA Processes Require Smg5 in Drosophila.
Genetics - 1 Aug 2018
Nelson Jonathan O, Förster Dominique, Frizzell Kimberly A, Luschnig Stefan, Metzstein Mark M
Abstract excerpt
The nonsense-mediated messenger RNA (mRNA) decay (NMD) pathway is a cellular quality control and post-transcriptional gene regulatory mechanism and is essential for viability in most multicellular organisms . A complex of proteins has been identified to be required for NMD function to occur; however, there is an incomplete understanding of the individual contributions of each of these factors to the NMD process....
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