Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.

Nucleic acids research - 1 Jan 2007

Luke Brian, Azzalin Claus M, Hug Nele, Deplazes Anna, Peter Matthias, Lingner Joachim

Abstract excerpt

The Smg proteins Smg5, Smg6 and Smg7 are involved in nonsense-mediated RNA decay (NMD) in metazoans, but no orthologs have been found in the budding yeast Saccharomyces cerevisiae. Sequence alignments reveal that yeast Ebs1p is similar in structure to the human Smg5-7, with highest homology to Sm...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Gene Expression Regulation, Fungal
Share to HeLa Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Biosynthesis

Share to RNA Helicases

Share to Saccharomyces cerevisiae Proteins

Share to Sirolimus

Share to Telomerase

Source

Open in PubMed Open full text

Identifiers

PMID: 17984081
DOI: 10.1093/nar/gkm912
PMCID: PMC2190716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17984081-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay.PMID 17984081Read ↗

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway.Semantic proximity Read ↗

SMG1:SMG8:SMG9-complex integrity maintains robustness of nonsense-mediated mRNA decaySemantic proximity Read ↗

SMG7 acts as a molecular link between mRNA surveillance and mRNA decay.Semantic proximity Read ↗

Multiple Nonsense-Mediated mRNA Processes Require Smg5 in Drosophila.Semantic proximity Read ↗

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4).Semantic proximity Read ↗

Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicaseSemantic proximity Read ↗

Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6.Semantic proximity Read ↗

A novel phosphorylation-independent interaction between SMG6 and UPF1 is essential for human NMD.Semantic proximity Read ↗

The Double Life of UPF1 in RNA and DNA Stability PathwaysSemantic proximity Read ↗

Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.Semantic proximity Read ↗

Nonsense-Mediated mRNA Decay Factor Functions in Human Health and DiseaseSemantic proximity Read ↗

Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.