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Article

Drosophila mutants show NMD pathway activity is reduced, but not eliminated, in the absence of Smg6.

RNA (New York, N.Y.) - 1 Aug 2012

Frizzell Kimberly A, Rynearson Shawn G, Metzstein Mark M

Abstract excerpt

The nonsense-mediated mRNA decay (NMD) pathway is best known for targeting mutant mRNAs containing premature termination codons for rapid degradation, but it is also required for regulation of many endogenous transcripts. Components of the NMD pathway were originally identified by forward genetic screens in yeast and Caenorhabditis elegans. In other organisms, the NMD pathway has been investigated by studying the...

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Source

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Identifiers

PMID: 22740637
DOI: 10.1261/rna.032821.112
PMCID: PMC3404369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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