[Genotoxicity assessment of 2-ethylhexyl acrylate using an in vivo Pig-a gene mutation assay integrated system].

Article

[Genotoxicity assessment of 2-ethylhexyl acrylate using an in vivo Pig-a gene mutation assay integrated system].

Wei sheng yan jiu = Journal of hygiene research - 1 Nov 2017

Huo Jiao, Ma Sijia, Chen Jinyao, Zhang Lishi

Abstract excerpt

OBJECTIVE: To verify the mutagenicity of 2-ethylhexyl acrylate( 2-EHA)using in vivo Pig-a gene mutation assay integrated system. METHODS: The SPF-grade male SD rats( n = 30) were randomized to six treatment groups, i. e. 4 treatment groups( 100, 200, 400 and 800 mg/kg), a control group( vegetable...

Topics

Acrylates
Animals
Comet Assay
Dose-Response Relationship, Drug
Erythrocytes
Male
Membrane Proteins
Micronucleus Tests
Mutagenicity Tests
Mutagens
Mutation
Rats
Rats, Sprague-Dawley

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