Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors.

Nucleic acids research - 6 Jul 2018

Takemoto Norihiko, Numata Itaru, Su'etsugu Masayuki, Miyoshi-Akiyama Tohru

Abstract excerpt

Mismatch repair (MMR) systems based on MutS eliminate mismatches originating from replication errors. Despite extensive conservation of mutS homologues throughout the three domains of life, Actinobacteria and some archaea do not have genes homologous to mutS. Here, we report that EndoMS/NucS of Corynebacterium glutamicum is the mismatch-specific endonuclease that functions cooperatively with a sliding clamp....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actinobacteria
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Base Pair Mismatch

Share to Corynebacterium glutamicum

Share to DNA-Directed DNA Polymerase

Share to DNA Replication

Share to Endodeoxyribonucleases

Share to Genes, Bacterial

Source

Open in PubMed Open full text

Identifiers

PMID: 29878158
DOI: 10.1093/nar/gky481
PMCID: PMC6159521

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacterial EndoMS/NucS acts as a clamp-mediated mismatch endonuclease to prevent asymmetric accumulation of replication errors.PMID 29878158Read ↗

Activation of the mismatch-specific endonuclease EndoMS/NucS by the replication clamp is required for high fidelity DNA replication.Semantic proximity Read ↗

Control of Genome Stability by EndoMS/NucS-Mediated Non-Canonical Mismatch RepairSemantic proximity Read ↗

Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS.Semantic proximity Read ↗

Engineering of the DNA replication and repair machinery to develop binary mutators for rapid genome evolution of Corynebacterium glutamicum.Semantic proximity Read ↗

The unique role of nucS-mediated noncanonical mismatch repair in Mycobacterium tuberculosis resistance evolution.Semantic proximity Read ↗

The SOS Error-Prone DNA Polymerase V Mutasome and β-Sliding Clamp Acting in Concert on Undamaged DNA and during Translesion Synthesis.Semantic proximity Read ↗

Identification of a mismatch-specific endonuclease in hyperthermophilic Archaea.Semantic proximity Read ↗

DNA MISMATCH REPAIRSemantic proximity Read ↗

The endonuclease domain of MutL interacts with the β sliding clamp.Semantic proximity Read ↗

A multilayered repair system protects the mycobacterial chromosome from endogenous and antibiotic-induced oxidative damage.Semantic proximity Read ↗

Mispair-bound human MutS–MutL complex triggers DNA incisions and activates mismatch repairSemantic proximity Read ↗

The alternating ATPase domains of MutS control DNA mismatch repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.