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DNA MISMATCH REPAIR

17 Mar 2005

Abstract excerpt

DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication and escape proofreading. MMR proteins also participate in many other DNA transactions, such that inactivation of MMR can have wide-ranging biological consequences, which can be either beneficial or detrimental. We begin this review by briefly considering the multiple functions of MMR proteins...

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PMID: 15952900
DOI: 10.1146/annurev.biochem.74.082803.133243

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