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Article

Local sequence features that influence AP-1 cis-regulatory activity.

Genome research - 1 Feb 2018

Chaudhari Hemangi G, Cohen Barak A

Abstract excerpt

In the genome, most occurrences of transcription factor binding sites (TFBS) have no cis-regulatory activity, which suggests that flanking sequences contain information that distinguishes functional from nonfunctional TFBS. We interrogated the role of flanking sequences near Activator Protein 1 (AP-1) binding sites that reside in DNase I Hypersensitive Sites (DHS) and regions annotated as Enhancers. In these...

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Identifiers

PMID: 29305491
DOI: 10.1101/gr.226530.117
PMCID: PMC5793781

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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