Article

Short DNA sequence patterns accurately identify broadly active human enhancers

2017-02-26

Abstract excerpt

<h4>ABSTRACT</h4> Enhancers are DNA regulatory elements that influence gene expression. There is substantial diversity in enhancers’ activity patterns: some enhancers drive expression in a single cellular context, while others are active across many. Sequence characteristics, such as transcription factor (TF) binding motifs, influence the activity patterns of regulatory sequences; however, the regulatory logic th...

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Literature Corpus work: 1fb85ab1-bf2e-5593-9881-e7810dbbb9b5
DOI: 10.1101/111955

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