Article

Sequence determinants of human gene regulatory elements

2021-03-18

Abstract excerpt

DNA determines where and when genes are expressed, but the full set of sequence determinants that control gene expression is not known. To obtain a global and unbiased view of the relative importance of different sequence determinants in gene expression, we measured transcriptional activity of DNA sequences that are in aggregate ∼100 times longer than the human genome in three different cell types. We show that en...

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Literature Corpus work: e948dba8-e222-5a62-b73a-65396fac1cc9
DOI: 10.1101/2021.03.18.435942

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