Article

A Bag-Of-Motif Model Captures Cell States at Distal Regulatory Sequences

2024-01-03

Abstract excerpt

Deciphering the intricate regulatory code governing cell-type-specific gene expression is a fundamental goal in genetics. Current methods struggle to capture the complex interplay between gene distal regulatory sequences and cell context. We developed a computational approach, BOM (Bag-of-Motifs), which represents cis-regulatory sequences by the type and number of TF binding motifs it contains, irrespective of mot...

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Identifiers and source

Literature Corpus work: 37505fb0-0650-57d8-808c-e0e05dd88a01
DOI: 10.1101/2024.01.03.574012

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