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Article

From remote enhancers to gene regulation: charting the genome's regulatory landscapes.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 1 Jan 2013

Symmons Orsolya, Spitz François

Abstract excerpt

Vertebrate genes are characterized by the presence of cis-regulatory elements located at great distances from the genes they control. Alterations of these elements have been implicated in human diseases and evolution, yet little is known about how these elements interact with their surrounding sequences. A recent survey of the mouse genome with a regulatory sensor showed that the regulatory activities of these...

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Share to Chromosomes, Mammalian
Share to DNA Transposable Elements

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enhancer Elements, Genetic

Share to Evolution, Molecular

Share to Gene Expression Regulation, Developmental

Share to Gene Regulatory Networks

Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 23650632
DOI: 10.1098/rstb.2012.0358
PMCID: PMC3682723

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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