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Article

Cardiac-Specific Bdh1 Overexpression Ameliorates Oxidative Stress and Cardiac Remodeling in Pressure Overload-Induced Heart Failure.

Circulation. Heart failure - 1 Dec 2017

Uchihashi Motoki, Hoshino Atsushi, Okawa Yoshifumi, Ariyoshi Makoto, Kaimoto Satoshi, Tateishi Shuhei, Ono Kazunori, Yamanaka Ryoetsu, Hato Daichi, Fushimura Yohei, Honda Sakiko, Fukai Kuniyoshi, Higuchi Yusuke, Ogata Takehiro, Iwai-Kanai Eri, Matoba Satoaki

Abstract excerpt

BACKGROUND: Energy starvation and the shift of energy substrate from fatty acids to glucose is the hallmark of metabolic remodeling during heart failure progression. However, ketone body metabolism in the failing heart has not been fully investigated. METHODS AND RESULTS: Microarray data analysis and mitochondrial isobaric tags for relative and absolute quantification proteomics revealed that the expression of...

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PMID: 29242353
DOI: 10.1161/CIRCHEARTFAILURE.117.004417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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