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Article

Hepatic Ketogenesis Attenuates Cardiac Hypertrophy via Metabolic Reprogramming

2026-02-02

Abstract excerpt

<h4>Background</h4> Heart failure with preserved ejection fraction (HfpEF) is increasingly recognized as a multisystem disorder linked to the cardiovascular-kidney-metabolic (CKM) syndrome. While the falling heart undergoes metabolic reprogramming, the interorgan crosstalk regulating myocardial substrate preference in HFpEF remains elusive. We aimed to clarify the role of systemic and local ketogenesis in the pat...

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Literature Corpus work
68035f45-c55f-5a19-8659-9e4e08dfde4c
DOI
10.64898/2026.01.30.702687
Open publication

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Hepatic Ketogenesis Attenuates Cardiac Hypertrophy via Metabolic ReprogrammingDOI 10.64898/2026.01.30.702687
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