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Article

Elucidating the Biological Roles of Insulin and Its Receptor in Murine Intestinal Growth and Function.

Endocrinology - 1 Aug 2017

Jensen Stina Rikke, Wheeler Sarah E, Hvid Henning, Ahnfelt-Rønne Jonas, Hansen Bo Falck, Nishimura Erica, Olsen Grith Skytte, Brubaker Patricia L

Abstract excerpt

The role of the intestinal insulin receptor (IR) is not well understood. We therefore explored the effect of insulin (300 nmol/kg per day for 12 days) on the intestine in sex-matched C57Bl/6J mice. The intestinal and metabolic profiles were also characterized in male and female intestinal-epithelial IR knockout (IE-irKO) mice compared with all genetic controls on a chow diet or Western diet (WD) for 4 to 12...

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Identifiers

PMID: 28591779
DOI: 10.1210/en.2017-00195

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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