Conserved insulin signaling in the regulation of oocyte growth, development, and maturation

Abstract excerpt

Insulin signaling regulates various aspects of physiology, such as glucose homeostasis and aging, and is a key determinant of female reproduction in metazoans. That insulin signaling is crucial for female reproductive health is clear from clinical data linking hyperinsulinemic and hypoinsulinemic condition with certain types of ovarian dysfunction, such as altered steroidogenesis, polycystic ovary syndrome, and...

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• Share to Genetics, Aging, and Longevity in Model Organisms
• Share to Ovarian function and disorders
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